| Contents per vial | 10 mg |
|---|---|
| Form | Lyophilized powder |
| Packaging | Sealed glass vial |
| Purity | 98,26 % |
| Storage | 2–8 °C, keep dry and protect from light |
| Molecular formula | C37H51N9O10S |
| Molecular weight | 813,92 g/mol |
| Sequence or structure | Met–Glu–His–Phe–Pro–Gly–Pro (MEHFPGP) |
| CAS | 80714-61-0 |
| Intended use | For laboratory research only |
About this product
Semax is a synthetic peptide derived from a fragment of ACTH, which is mainly being investigated for neuroprotective and cognitive effects. Research is devoted to memory, learning, response of nervous tissue to ischemic damage and neurotrophic factors. Semax does not have classic ACTH corticotropic activity. It is particularly interesting as a tool for neuroplasticity research.
What is SEMAX?
From a scientific perspective, SEMAX represents a substance classified as a synthetic peptide or peptide analog. Its experimental profile is mainly assessed through memory and learning, neuroprotection, BDNF and neurotrophic factors, dopaminergic and serotonergic signaling, while individual research questions can use different cell, tissue or organismal models. Binding to target structures, subsequent signaling and changes in selected biological indicators are monitored.
Mechanism of action under investigation
Semax affects neurotrophic and neurotransmitter pathways without the typical hormonal activity of ACTH. In particular, the modulation of BDNF and neuroplasticity mechanisms is investigated.
MAIN AREAS OF RESEARCH
• Memory and learning: Semax is studied in relation to learning, memory and adaptation of the nervous system to stress.
• Neuroprotection: Experimental models evaluate the protection of nerve cells during oxygen deprivation, ischemic damage and other forms of cellular stress.
• BDNF and neurotrophic factors: Research looks at changes in BDNF and other growth signals that support neuronal plasticity, survival and function.
• Neurotransmitter signaling: Semax is also being investigated for changes in the dopamine, serotonin and peptide systems that affect the function of brain circuits.
Research findings to date
Work to date with SEMAX has focused on areas including memory and learning, neuroprotection, BDNF and neurotrophic factors, dopaminergic and serotonergic signaling. Research is devoted to memory, learning, response of nervous tissue to ischemic damage and neurotrophic factors.
