| Contents per vial | 10 mg |
|---|---|
| Form | Lyophilized powder |
| Packaging | Sealed glass vial |
| Purity | 98 % (HPLC) |
| Storage | 2–8 °C, keep dry and protect from light |
| Molecular formula | C46H56N12O6 |
| Molecular weight | 873,01 g/mol |
| Sequence or structure | His–D-Trp–Ala–Trp–D-Phe–Lys–NH2 |
| CAS | 87616-84-0 |
| Intended use | For laboratory research only |
About this product
GHRP-6 is a synthetic peptide from the group of growth hormone secretagogues. It activates the ghrelin receptor and is known for its significant stimulation of GH and its effect on the feeling of hunger. Research is focused on the GH/IGF-1 hormonal axis, appetite and metabolic responses. Compared to some newer secretagogues, it is less selective. Therefore, its broader neuroendocrine response is also being investigated.
What is GHRP-6?
GHRP-6 is characterized in this portfolio as a synthetic peptide or peptide analog intended for controlled laboratory investigation. Scientific interest is focused on growth hormone secretion, appetite and hunger, GH/IGF-1 axis, neuroendocrine effects and related biochemical or receptor processes. Changes in predetermined markers, functional responses and signaling pathways are compared in experimental protocols.
Mechanism of action under investigation
GHRP-6 is a GHS-R1a agonist. By activating the ghrelin receptor, it supports the secretion of GH and at the same time intervenes in the central pathways that regulate hunger.
MAIN AREAS OF RESEARCH
• Growth Hormone Secretion: GHRP-6 is a ghrelin receptor agonist and is being investigated for growth hormone stimulation that is highly synergistic with natural GHRH.
• Appetite and hunger: GHRP-6 is known to have a stronger effect on the ghrelin mechanisms of hunger, so the regulation of food intake is also being investigated.
• GH/IGF-1 axis: Research looks at how repeated GHSR activation affects GH pulses and subsequent IGF-1 signaling.
• Neuroendocrine Mechanisms: GHRP-6 helps investigate the cooperation of the ghrelin system with the hypothalamus and pituitary gland in controlling the hormonal response.
Research findings to date
Results should be assessed according to the level of evidence: cell and animal models. Research is focused on the GH/IGF-1 hormonal axis, appetite and metabolic responses. GHRP-6 can significantly affect appetite and hormone signaling. Changes in cortisol, prolactin and insulin sensitivity are also monitored in the research.
