{"id":549,"date":"2026-10-27T12:16:28","date_gmt":"2026-10-27T12:16:28","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/vip-10mg\/"},"modified":"2026-10-27T12:16:28","modified_gmt":"2026-10-27T12:16:28","slug":"vip-10mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/sk\/produkt\/vip-10mg\/","title":{"rendered":"Vasoactive Intestinal Peptide (VIP) 10 mg"},"content":{"rendered":"

VIP je prirodzen\u00fd neuropeptid a horm\u00f3n s v\u00fdrazn\u00fdmi \u00fa\u010dinkami na cievy, hladk\u00e9 svalstvo, tr\u00e1viaci trakt, p\u013e\u00faca a imunitn\u00fa signaliz\u00e1ciu. Jeho n\u00e1zov vych\u00e1dza zo schopnosti roz\u0161irova\u0165 cievy, no biologick\u00e9 p\u00f4sobenie je omnoho \u0161ir\u0161ie. V\u00fdskum sa venuje z\u00e1palu, bronchomotorike, \u010drevnej sekr\u00e9cii a neuroimunitnej komunik\u00e1cii. Ke\u010f\u017ee VIP p\u00f4sob\u00ed v mnoh\u00fdch org\u00e1noch, je v\u00fdznamn\u00fdm modelom pleiotropnej peptidovej signaliz\u00e1cie.<\/p>\n

\u010co je VIP \u2013 Vasoactive Intestinal Peptide?<\/h2>\n

Z odborn\u00e9ho h\u013eadiska predstavuje VIP \u2013 Vasoactive Intestinal Peptide l\u00e1tku zaraden\u00fa ako syntetick\u00fd peptid alebo peptidov\u00fd anal\u00f3g. Jej experiment\u00e1lny profil sa posudzuje najm\u00e4 cez vazodilat\u00e1ciu, d\u00fdchacie cesty, tr\u00e1viaci trakt, imunitn\u00e1 regul\u00e1cia, pri\u010dom jednotliv\u00e9 v\u00fdskumn\u00e9 ot\u00e1zky m\u00f4\u017eu vyu\u017e\u00edva\u0165 rozdielne bunkov\u00e9, tkanivov\u00e9 alebo organizmov\u00e9 modely. Sleduje sa v\u00e4zba na cie\u013eov\u00e9 \u0161trukt\u00fary, nadv\u00e4zuj\u00faca signaliz\u00e1cia a zmena vybran\u00fdch biologick\u00fdch ukazovate\u013eov.<\/p>\n

Mechanizmus sk\u00faman\u00e9ho p\u00f4sobenia<\/h2>\n

VIP aktivuje receptory VPAC1 a VPAC2 (a s ni\u017e\u0161ou afinitou PAC1), ktor\u00e9 zvy\u0161uj\u00fa cAMP a menia aktivitu hladk\u00e9ho svalstva, sekr\u00e9ciu a imunitn\u00fa odpove\u010f.<\/p>\n

Hlavn\u00e9 oblasti v\u00fdskumu<\/h2>\n

\u2022  Vazodilat\u00e1cia: <\/strong>VIP je prirodzen\u00fd neuropeptid sk\u00faman\u00fd pre siln\u00fd vplyv na uvo\u013enenie hladkej svaloviny ciev a regul\u00e1ciu cievneho tonusu.<\/p>\n

\u2022  D\u00fdchacie cesty: <\/strong>V\u00fdskum sleduje bronchodilat\u00e1ciu, sekr\u00e9ciu hlienu a z\u00e1palov\u00e9 procesy v p\u013e\u00facach a d\u00fdchac\u00edch cest\u00e1ch.<\/p>\n

\u2022  Tr\u00e1viaci trakt: <\/strong>VIP reguluje pohyb \u010dreva, sekr\u00e9ciu tekut\u00edn a komunik\u00e1ciu medzi nervov\u00fdm syst\u00e9mom a \u010drevnou stenou.<\/p>\n

\u2022  Imunitn\u00e1 regul\u00e1cia: <\/strong>Peptid ovplyv\u0148uje aktivitu viacer\u00fdch imunitn\u00fdch buniek a cytok\u00ednov, preto sa sk\u00fama v modeloch z\u00e1palov\u00fdch a autoimunitn\u00fdch procesov.<\/p>\n

\u2022  Neuroendokrinn\u00e1 signaliz\u00e1cia: <\/strong>VIP funguje ako neurotransmiter aj lok\u00e1lny sign\u00e1l a pom\u00e1ha sk\u00fama\u0165 prepojenie nervovej, hormon\u00e1lnej a imunitnej regul\u00e1cie.<\/p>\n

Doteraj\u0161ie zistenia v\u00fdskumu<\/h2>\n

Doteraj\u0161ie pr\u00e1ce pri l\u00e1tke VIP \u2013 Vasoactive Intestinal Peptide sa venuj\u00fa oblastiam, medzi ktor\u00e9 patria vazodilat\u00e1cia, d\u00fdchacie cesty, tr\u00e1viaci trakt, imunitn\u00e1 regul\u00e1cia, neuroendokrinn\u00e1 signaliz\u00e1cia. V\u00fdsledky treba posudzova\u0165 pod\u013ea \u00farovne d\u00f4kazov: bunkov\u00e9 a zvieracie modely.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produkt Vasoactive Intestinal Peptide (VIP) sa dod\u00e1va ako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. Ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny v\u00fdskum. Nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.<\/p>\n","protected":false},"featured_media":545,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[22],"product_tag":[39,40,41],"class_list":["post-549","product","type-product","status-publish","has-post-thumbnail","product_cat-vyskumne-serie","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nVasoactive Intestinal Peptide (VIP) 10 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/sk\/produkt\/vip-10mg\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vasoactive Intestinal Peptide (VIP) 10 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt Vasoactive Intestinal Peptide (VIP) sa dod\u00e1va ako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. 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