{"id":380,"date":"2026-10-27T12:15:15","date_gmt":"2026-10-27T12:15:15","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/foxo4-dri-10mg\/"},"modified":"2026-10-27T12:15:15","modified_gmt":"2026-10-27T12:15:15","slug":"foxo4-dri-10mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/","title":{"rendered":"FOXO4-DRI 10 mg"},"content":{"rendered":"

FOXO4-DRI je experiment\u00e1lny peptid navrhnut\u00fd na naru\u0161enie interakcie medzi FOXO4 a p53 v senescentn\u00fdch bunk\u00e1ch. Preklinick\u00fd v\u00fdskum sk\u00fama, \u010di t\u00fdm mo\u017eno selekt\u00edvne podpori\u0165 apopt\u00f3zu ur\u010dit\u00fdch starn\u00facich buniek. Z\u00e1ujem vznikol v oblasti senolyt\u00edk a biologick\u00e9ho starnutia.<\/p>\n

\u010co je FOXO4-DRI?<\/h2>\n

FOXO4-DRI sa zara\u010fuje medzi l\u00e1tky typu \u201esyntetick\u00fd peptid alebo peptidov\u00fd anal\u00f3g\u201c a v odbornom v\u00fdskume sa hodnot\u00ed v s\u00favislosti s oblas\u0165ami ako senescentn\u00e9 bunky, foxo4-p53 interakcia, tkanivov\u00e9 starnutie, senolytick\u00fd v\u00fdskum. Pozornos\u0165 sa venuje jeho interakcii s pr\u00edslu\u0161n\u00fdmi receptormi, enz\u00fdmami alebo bunkov\u00fdmi dr\u00e1hami a n\u00e1sledn\u00fdm zmen\u00e1m merate\u013en\u00fdch laborat\u00f3rnych parametrov.<\/p>\n

Mechanizmus sk\u00faman\u00e9ho p\u00f4sobenia<\/h2>\n

FOXO4-DRI m\u00e1 naru\u0161i\u0165 v\u00e4zbu FOXO4 na p53. V senescentn\u00fdch bunk\u00e1ch to m\u00f4\u017ee presun\u00fa\u0165 p53 a podpori\u0165 apoptotick\u00fd program; tento mechanizmus je preklinick\u00fd.<\/p>\n

Hlavn\u00e9 oblasti v\u00fdskumu<\/h2>\n

\u2022  Senescentn\u00e9 bunky: <\/strong>FOXO4-DRI bol navrhnut\u00fd na v\u00fdskum buniek, ktor\u00e9 prestali deli\u0165, ale zost\u00e1vaj\u00fa metabolicky akt\u00edvne a m\u00f4\u017eu ovplyv\u0148ova\u0165 okolit\u00e9 tkanivo.<\/p>\n

\u2022  Interakcia FOXO4\u2013p53: <\/strong>Peptid nar\u00fa\u0161a v\u00e4zbu medzi FOXO4 a p53, ktor\u00e1 v senescentn\u00fdch bunk\u00e1ch pom\u00e1ha udr\u017eiava\u0165 p53 mimo mechanizmov ved\u00facich k bunkovej smrti.<\/p>\n

\u2022  Senolytick\u00fd v\u00fdskum: <\/strong>Predklinick\u00e9 pr\u00e1ce sk\u00famaj\u00fa selekt\u00edvne odstr\u00e1nenie \u010dasti senescentn\u00fdch buniek a n\u00e1sledn\u00e9 zmeny funkcie tkan\u00edv.<\/p>\n

\u2022  Tkanivov\u00e9 starnutie: <\/strong>V\u00fdskum hodnot\u00ed, \u010di zn\u00ed\u017eenie z\u00e1\u0165a\u017ee senescentn\u00fdmi bunkami ovplyv\u0148uje vekovo podmienen\u00e9 zmeny org\u00e1nov; klinick\u00e9 \u00fadaje u \u013eud\u00ed zatia\u013e ch\u00fdbaj\u00fa.<\/p>\n

Doteraj\u0161ie zistenia v\u00fdskumu<\/h2>\n

V\u00fdsledky treba posudzova\u0165 pod\u013ea \u00farovne d\u00f4kazov: bunkov\u00e9 a zvieracie. Preklinick\u00fd v\u00fdskum sk\u00fama, \u010di t\u00fdm mo\u017eno selekt\u00edvne podpori\u0165 apopt\u00f3zu ur\u010dit\u00fdch starn\u00facich buniek. Neexistuje klinicky potvrden\u00fd anti-aging \u00fa\u010dinok u \u013eud\u00ed.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produkt FOXO4-DRI sa dod\u00e1va ako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. Ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny v\u00fdskum. Nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.<\/p>\n","protected":false},"featured_media":376,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[20],"product_tag":[39,40,41],"class_list":["post-380","product","type-product","status-publish","has-post-thumbnail","product_cat-dlhovekost-a-anti-aging","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nFOXO4-DRI 10 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FOXO4-DRI 10 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt FOXO4-DRI sa dod\u00e1va ako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. Ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny v\u00fdskum. Nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/\" \/>\n<meta property=\"og:site_name\" content=\"VirexionLabs.net\" \/>\n<meta property=\"og:image\" content=\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Cena\" \/>\n\t<meta name=\"twitter:data1\" content=\"199,00 €\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dostupnos\u0165\" \/>\n\t<meta name=\"twitter:data2\" content=\"Na sklade\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/\",\"url\":\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/\",\"name\":\"FOXO4-DRI 10 mg - VirexionLabs.net\",\"isPartOf\":{\"@id\":\"https:\/\/virexionlabs.net\/sk\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp\",\"datePublished\":\"2026-10-27T12:15:15+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#breadcrumb\"},\"inLanguage\":\"sk-SK\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"sk-SK\",\"@id\":\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#primaryimage\",\"url\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp\",\"contentUrl\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp\",\"width\":1024,\"height\":1024,\"caption\":\"FOXO4-DRI 10 mg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/virexionlabs.net\/sk\/domov-2\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Obchod\",\"item\":\"https:\/\/virexionlabs.net\/sk\/obchod\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"FOXO4-DRI 10 mg\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/virexionlabs.net\/sk\/#website\",\"url\":\"https:\/\/virexionlabs.net\/sk\/\",\"name\":\"VirexionLabs.com\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/virexionlabs.net\/sk\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/virexionlabs.net\/sk\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"sk-SK\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/virexionlabs.net\/sk\/#organization\",\"name\":\"VirexionLabs.com\",\"url\":\"https:\/\/virexionlabs.net\/sk\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sk-SK\",\"@id\":\"https:\/\/virexionlabs.net\/sk\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png\",\"contentUrl\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png\",\"width\":2172,\"height\":724,\"caption\":\"VirexionLabs.com\"},\"image\":{\"@id\":\"https:\/\/virexionlabs.net\/sk\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<meta property=\"product:price:amount\" content=\"199.00\" \/>\n<meta property=\"product:price:currency\" content=\"EUR\" \/>\n<meta property=\"og:availability\" content=\"instock\" \/>\n<meta property=\"product:availability\" content=\"instock\" \/>\n<meta property=\"product:retailer_item_id\" content=\"VX-FOXO4-DRI-10MG\" \/>\n<meta property=\"product:condition\" content=\"new\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"FOXO4-DRI 10 mg - VirexionLabs.net","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/","og_locale":"sk_SK","og_type":"article","og_title":"FOXO4-DRI 10 mg","og_description":"Produkt FOXO4-DRI sa dod\u00e1va ako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. Ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny v\u00fdskum. Nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.","og_url":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/","og_site_name":"VirexionLabs.net","og_image":[{"width":1024,"height":1024,"url":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp","type":"image\/webp"}],"twitter_card":"summary_large_image","twitter_misc":{"Cena":"199,00 €","Dostupnos\u0165":"Na sklade"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/","url":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/","name":"FOXO4-DRI 10 mg - VirexionLabs.net","isPartOf":{"@id":"https:\/\/virexionlabs.net\/sk\/#website"},"primaryImageOfPage":{"@id":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#primaryimage"},"image":{"@id":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#primaryimage"},"thumbnailUrl":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp","datePublished":"2026-10-27T12:15:15+00:00","breadcrumb":{"@id":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#breadcrumb"},"inLanguage":"sk-SK","potentialAction":[{"@type":"ReadAction","target":["https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/"]}]},{"@type":"ImageObject","inLanguage":"sk-SK","@id":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#primaryimage","url":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp","contentUrl":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/40_FOXO4-DRI_10_mg-muwpd47q-k66i-1024w.webp","width":1024,"height":1024,"caption":"FOXO4-DRI 10 mg"},{"@type":"BreadcrumbList","@id":"https:\/\/virexionlabs.net\/sk\/produkt\/foxo4-dri-10mg\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/virexionlabs.net\/sk\/domov-2\/"},{"@type":"ListItem","position":2,"name":"Obchod","item":"https:\/\/virexionlabs.net\/sk\/obchod\/"},{"@type":"ListItem","position":3,"name":"FOXO4-DRI 10 mg"}]},{"@type":"WebSite","@id":"https:\/\/virexionlabs.net\/sk\/#website","url":"https:\/\/virexionlabs.net\/sk\/","name":"VirexionLabs.com","description":"","publisher":{"@id":"https:\/\/virexionlabs.net\/sk\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/virexionlabs.net\/sk\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"sk-SK"},{"@type":"Organization","@id":"https:\/\/virexionlabs.net\/sk\/#organization","name":"VirexionLabs.com","url":"https:\/\/virexionlabs.net\/sk\/","logo":{"@type":"ImageObject","inLanguage":"sk-SK","@id":"https:\/\/virexionlabs.net\/sk\/#\/schema\/logo\/image\/","url":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png","contentUrl":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png","width":2172,"height":724,"caption":"VirexionLabs.com"},"image":{"@id":"https:\/\/virexionlabs.net\/sk\/#\/schema\/logo\/image\/"}}]},"product_price_amount":"199.00","product_price_currency":"EUR","og_availability":"instock","product_availability":"instock","product_retailer_item_id":"VX-FOXO4-DRI-10MG","product_condition":"new"},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/product\/380","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/comments?post=380"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/media\/376"}],"wp:attachment":[{"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/media?parent=380"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/product_brand?post=380"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/product_cat?post=380"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/virexionlabs.net\/sk\/wp-json\/wp\/v2\/product_tag?post=380"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}