{"id":355,"date":"2026-10-27T12:15:04","date_gmt":"2026-10-27T12:15:04","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/cjc-without-dac-5mg\/"},"modified":"2026-10-27T12:15:04","modified_gmt":"2026-10-27T12:15:04","slug":"cjc-without-dac-5mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/sk\/produkt\/cjc-without-dac-5mg\/","title":{"rendered":"CJC without DAC 5 mg"},"content":{"rendered":"

CJC-1295 bez DAC ozna\u010duje krat\u0161ie p\u00f4sobiacu GHRH-anal\u00f3gov\u00fa molekulu bez Drug Affinity Complexu. Sk\u00fama sa pre stimul\u00e1ciu pulzn\u00e9ho uvo\u013e\u0148ovania rastov\u00e9ho horm\u00f3nu a osi GH\/IGF-1. Bez DAC nem\u00e1 pred\u013a\u017een\u00fa album\u00ednov\u00fa v\u00e4zbu typick\u00fa pre CJC-1295 with DAC. V\u00fdskumn\u00fd v\u00fdznam spo\u010d\u00edva v kr\u00e1tkodobej\u0161ej GHRH receptorovej stimul\u00e1cii.<\/p>\n

\u010co je CJC-1295 bez DAC?<\/h2>\n

CJC-1295 bez DAC sa zara\u010fuje medzi l\u00e1tky typu \u201esyntetick\u00fd peptid alebo peptidov\u00fd anal\u00f3g\u201c a v odbornom v\u00fdskume sa hodnot\u00ed v s\u00favislosti s oblas\u0165ami ako sekr\u00e9cia rastov\u00e9ho horm\u00f3nu, pulzatilita GH, IGF-1. Pozornos\u0165 sa venuje jeho interakcii s pr\u00edslu\u0161n\u00fdmi receptormi, enz\u00fdmami alebo bunkov\u00fdmi dr\u00e1hami a n\u00e1sledn\u00fdm zmen\u00e1m merate\u013en\u00fdch laborat\u00f3rnych parametrov.<\/p>\n

Mechanizmus sk\u00faman\u00e9ho p\u00f4sobenia<\/h2>\n

Molekula aktivuje GHRH receptor a cAMP signaliz\u00e1ciu v hypof\u00fdze. Absencia DAC znamen\u00e1 krat\u0161iu cirkul\u00e1ciu a bez album\u00ednovej v\u00e4zby typickej pre DAC variant.<\/p>\n

Hlavn\u00e9 oblasti v\u00fdskumu<\/h2>\n

\u2022  Sekr\u00e9cia rastov\u00e9ho horm\u00f3nu: <\/strong>CJC-1295 bez DAC je kr\u00e1tkodobej\u0161\u00ed GHRH anal\u00f3g sk\u00faman\u00fd pre stimul\u00e1ciu uvo\u013e\u0148ovania rastov\u00e9ho horm\u00f3nu cez GHRH receptor.<\/p>\n

\u2022  Pulzatilita GH: <\/strong>Krat\u0161ie p\u00f4sobenie umo\u017e\u0148uje sk\u00fama\u0165 hormon\u00e1lnu odpove\u010f bli\u017e\u0161iu jednotliv\u00fdm pulzom GH ne\u017e pri dlhodobo p\u00f4sobiacej DAC forme.<\/p>\n

\u2022  IGF-1: <\/strong>V\u00fdskum sleduje, ako stimul\u00e1cia GH n\u00e1sledne men\u00ed IGF-1 a \u010fal\u0161ie ukazovatele osi rastov\u00e9ho horm\u00f3nu.<\/p>\n

\u2022  Rozdiel oproti DAC forme: <\/strong>Bez Drug Affinity Complexu sa molekula nevia\u017ee dlhodobo na album\u00edn, preto m\u00e1 odli\u0161n\u00fd farmakokinetick\u00fd profil od CJC-1295 s DAC.<\/p>\n

Doteraj\u0161ie zistenia v\u00fdskumu<\/h2>\n

V\u00fdsledky treba posudzova\u0165 pod\u013ea \u00farovne d\u00f4kazov: bunkov\u00e9 a zvieracie modely. V\u00fdskumn\u00fd v\u00fdznam spo\u010d\u00edva v kr\u00e1tkodobej\u0161ej GHRH receptorovej stimul\u00e1cii. Pri l\u00e1tkach ovplyv\u0148uj\u00facich os rastov\u00e9ho horm\u00f3nu sa vo v\u00fdskume sleduj\u00fa napr\u00edklad reakcie v mieste podania, boles\u0165 hlavy, zmeny apet\u00edtu, zadr\u017eiavanie tekut\u00edn a hormon\u00e1lne zmeny.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produkt CJC without DAC sa dod\u00e1va ako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. Ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny v\u00fdskum. Nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.<\/p>\n","protected":false},"featured_media":351,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[16],"product_tag":[39,40,41],"class_list":["post-355","product","type-product","status-publish","has-post-thumbnail","product_cat-regeneracia-a-vykon","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nCJC without DAC 5 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/sk\/produkt\/cjc-without-dac-5mg\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CJC without DAC 5 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt CJC without DAC sa dod\u00e1va ako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. 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