{"id":339,"date":"2026-10-27T12:14:56","date_gmt":"2026-10-27T12:14:56","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/aod-9604-5mg\/"},"modified":"2026-10-27T12:14:56","modified_gmt":"2026-10-27T12:14:56","slug":"aod-9604-5mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/sk\/produkt\/aod-9604-5mg\/","title":{"rendered":"AOD-9604 5 mg"},"content":{"rendered":"<p>AOD-9604 je modifikovan\u00fd fragment C-koncovej \u010dasti \u013eudsk\u00e9ho rastov\u00e9ho horm\u00f3nu vyv\u00edjan\u00fd najm\u00e4 pre v\u00fdskum metabolizmu tukov a obezity. Bol navrhnut\u00fd tak, aby napodob\u0148oval \u010das\u0165 lipolytick\u00fdch \u00fa\u010dinkov GH bez plnej rastovej aktivity horm\u00f3nu. Preklinick\u00e9 pr\u00e1ce ukazovali vplyv na lipol\u00fdzu a&nbsp;lipogen\u00e9zu. Nesk\u00f4r sa sk\u00famal aj v \u010fal\u0161\u00edch tkanivov\u00fdch modeloch.<\/p>\n<h2>\u010co je AOD-9604?<\/h2>\n<p>AOD-9604 sa zara\u010fuje medzi l\u00e1tky typu \u201esyntetick\u00fd peptid alebo peptidov\u00fd anal\u00f3g\u201c a v odbornom v\u00fdskume sa hodnot\u00ed v s\u00favislosti s oblas\u0165ami ako metabolizmus tukov, lipol\u00fdza, lipogen\u00e9za, telesn\u00e1 hmotnos\u0165. Pozornos\u0165 sa venuje jeho interakcii s pr\u00edslu\u0161n\u00fdmi receptormi, enz\u00fdmami alebo bunkov\u00fdmi dr\u00e1hami a n\u00e1sledn\u00fdm zmen\u00e1m merate\u013en\u00fdch laborat\u00f3rnych parametrov.<\/p>\n<h2>Mechanizmus sk\u00faman\u00e9ho p\u00f4sobenia<\/h2>\n<p>AOD-9604 je modifikovan\u00fd fragment GH 176-191. M\u00e1 zachova\u0165 metabolick\u00fa signaliz\u00e1ciu spojen\u00fa s tukom bez plnej aktiv\u00e1cie rastov\u00e9ho horm\u00f3nov\u00e9ho receptora.<\/p>\n<h2>Hlavn\u00e9 oblasti v\u00fdskumu<\/h2>\n<p><strong>\u2022&nbsp; Metabolizmus tukov: <\/strong>AOD-9604 je modifikovan\u00fd fragment C-koncovej \u010dasti rastov\u00e9ho horm\u00f3nu sk\u00faman\u00fd pre metabolick\u00e9 procesy v tukovom tkanive.<\/p>\n<p><strong>\u2022&nbsp; Lipol\u00fdza: <\/strong>Predklinick\u00fd v\u00fdskum sa venuje mobiliz\u00e1cii ulo\u017een\u00e9ho tuku a uvo\u013e\u0148ovaniu mastn\u00fdch kysel\u00edn z adipocytov.<\/p>\n<p><strong>\u2022&nbsp; Lipogen\u00e9za: <\/strong>S\u00fa\u010dasne sa sk\u00fama vplyv na tvorbu a ukladanie nov\u00fdch z\u00e1sob tuku, aby sa oddelili metabolick\u00e9 \u00fa\u010dinky od rastov\u00fdch \u00fa\u010dinkov cel\u00e9ho GH.<\/p>\n<p><strong>\u2022&nbsp; Telesn\u00e1 hmotnos\u0165: <\/strong>AOD-9604 bol sk\u00faman\u00fd aj v klinickom v\u00fdvoji pre obezitu, no dostupn\u00e9 v\u00fdsledky nepotvrdili konzistentn\u00fd klinick\u00fd \u00fa\u010dinok na redukciu hmotnosti.<\/p>\n<p><strong>\u2022&nbsp; Chrupavka: <\/strong>Samostatn\u00fd predklinick\u00fd smer sk\u00fama AOD-9604 v modeloch po\u0161kodenia chrupavky a&nbsp;osteoartr\u00f3zy.<\/p>\n<h2>Doteraj\u0161ie zistenia v\u00fdskumu<\/h2>\n<p>V\u00fdsledky treba posudzova\u0165 pod\u013ea \u00farovne d\u00f4kazov: bunkov\u00e9 a zvieracie. AOD-9604 je modifikovan\u00fd fragment C-koncovej \u010dasti \u013eudsk\u00e9ho rastov\u00e9ho horm\u00f3nu vyv\u00edjan\u00fd najm\u00e4 pre v\u00fdskum metabolizmu tukov a obezity. Preklinick\u00e9 pr\u00e1ce ukazovali vplyv na lipol\u00fdzu a lipogen\u00e9zu, no klinick\u00e9 v\u00fdsledky pri redukcii hmotnosti nepreuk\u00e1zali presved\u010div\u00fd \u00fa\u010dinok potrebn\u00fd na etablovan\u00fa lie\u010dbu obezity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Produkt AOD-9604 sa dod\u00e1va ako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. Ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny v\u00fdskum. Nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie.<\/p>\n","protected":false},"featured_media":335,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[17],"product_tag":[39,40,41],"class_list":["post-339","product","type-product","status-publish","has-post-thumbnail","product_cat-kontrola-hmotnosti","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.6 (Yoast SEO v25.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>AOD-9604 5 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/sk\/produkt\/aod-9604-5mg\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"AOD-9604 5 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt AOD-9604 sa dod\u00e1va ako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ok v uzavretej sklenenej vialke. 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