{"id":548,"date":"2026-10-27T12:16:27","date_gmt":"2026-10-27T12:16:27","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/vip-10mg\/"},"modified":"2026-10-27T12:16:27","modified_gmt":"2026-10-27T12:16:27","slug":"vip-10mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/cs\/produkt\/vip-10mg\/","title":{"rendered":"Vasoactive Intestinal Peptide (VIP) 10 mg"},"content":{"rendered":"

VIP je p\u0159irozen\u00fd neuropeptid a hormon s v\u00fdrazn\u00fdmi \u00fa\u010dinky na c\u00e9vy, hladk\u00e9 svalstvo, tr\u00e1vic\u00ed trakt, pl\u00edce a imunitn\u00ed signalizaci. Jeho n\u00e1zev vych\u00e1z\u00ed ze schopnosti roz\u0161i\u0159ovat c\u00e9vy, ale biologick\u00e9 p\u016fsoben\u00ed je mnohem \u0161ir\u0161\u00ed. V\u00fdzkum se v\u011bnuje z\u00e1n\u011btu, bronchomotorice, st\u0159evn\u00ed sekreci a neuroimunitn\u00ed komunikaci. Proto\u017ee VIP p\u016fsob\u00ed v mnoha org\u00e1nech, je v\u00fdznamn\u00fdm modelem pleiotropn\u00ed peptidov\u00e9 signalizace.<\/p>\n

Co je VIP \u2013 Vasoactive Intestinal Peptide?<\/h2>\n

Z odborn\u00e9ho hlediska p\u0159edstavuje VIP \u2013 Vasoactive Intestinal Peptide l\u00e1tku za\u0159azenou jako syntetick\u00fd peptid nebo peptidov\u00fd analog. Jej\u00ed experiment\u00e1ln\u00ed profil se posuzuje zejm\u00e9na p\u0159es vazodilataci, d\u00fdchac\u00ed cesty, tr\u00e1vic\u00ed trakt, imunitn\u00ed regulace, p\u0159i\u010dem\u017e jednotliv\u00e9 v\u00fdzkumn\u00e9 ot\u00e1zky mohou vyu\u017e\u00edvat rozd\u00edln\u00e9 bun\u011b\u010dn\u00e9, tk\u00e1\u0148ov\u00e9 nebo organismov\u00e9 modely. Sleduje se vazba na c\u00edlov\u00e9 struktury, navazuj\u00edc\u00ed signalizace a zm\u011bna vybran\u00fdch biologick\u00fdch ukazatel\u016f.<\/p>\n

Mechanismus zkouman\u00e9ho p\u016fsoben\u00ed<\/h2>\n

VIP aktivuje receptory VPAC1 a VPAC2 (a s ni\u017e\u0161\u00ed afinitou PAC1), kter\u00e9 zvy\u0161uj\u00ed cAMP a m\u011bn\u00ed aktivitu hladk\u00e9ho svalstva, sekreci a imunitn\u00ed odpov\u011b\u010f.<\/p>\n

Hlavn\u00ed oblasti v\u00fdzkumu<\/h2>\n

\u2022  Vazodilatace: <\/strong>VIP je p\u0159irozen\u00fd neuropeptid zkouman\u00fd pro siln\u00fd vliv na uvoln\u011bn\u00ed hladk\u00e9 svaloviny c\u00e9v a regulaci c\u00e9vn\u00edho tonu.<\/p>\n

\u2022  D\u00fdchac\u00ed cesty: <\/strong>V\u00fdzkum sleduje bronchodilataci, sekreci hlenu a z\u00e1n\u011btliv\u00e9 procesy v plic\u00edch a d\u00fdchac\u00edch cest\u00e1ch.<\/p>\n

\u2022  Tr\u00e1vic\u00ed trakt: <\/strong>VIP reguluje pohyb st\u0159eva, sekreci tekutin a komunikaci mezi nervov\u00fdm syst\u00e9mem a st\u0159evn\u00ed st\u011bnou.<\/p>\n

\u2022  Imunitn\u00ed regulace: <\/strong>Peptid ovliv\u0148uje aktivitu v\u00edce imunitn\u00edch bun\u011bk a cytokin\u016f, proto se zkoum\u00e1 v modelech z\u00e1n\u011btliv\u00fdch a autoimunitn\u00edch proces\u016f.<\/p>\n

\u2022  Neuroendokrinn\u00ed signalizace: <\/strong>VIP funguje jako neurotransmiter i lok\u00e1ln\u00ed sign\u00e1l a pom\u00e1h\u00e1 zkoumat propojen\u00ed nervov\u00e9, hormon\u00e1ln\u00ed a imunitn\u00ed regulace.<\/p>\n

Dosavadn\u00ed zji\u0161t\u011bn\u00ed v\u00fdzkumu<\/h2>\n

Dosavadn\u00ed pr\u00e1ce u l\u00e1tky VIP \u2013 Vasoactive Intestinal Peptide se v\u011bnuj\u00ed oblastem, mezi kter\u00e9 pat\u0159\u00ed vazodilatace, d\u00fdchac\u00ed cesty, tr\u00e1vic\u00ed trakt, imunitn\u00ed regulace, neuroendokrinn\u00ed signalizace. V\u00fdsledky je t\u0159eba posuzovat podle \u00farovn\u011b d\u016fkaz\u016f: bun\u011b\u010dn\u00e9 a zv\u00ed\u0159ec\u00ed modely.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produkt Vasoactive Intestinal Peptide (VIP) se dod\u00e1v\u00e1 jako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.<\/p>\n","protected":false},"featured_media":545,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[22],"product_tag":[39,40,41],"class_list":["post-548","product","type-product","status-publish","has-post-thumbnail","product_cat-vyskumne-serie","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nVasoactive Intestinal Peptide (VIP) 10 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/cs\/produkt\/vip-10mg\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vasoactive Intestinal Peptide (VIP) 10 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt Vasoactive Intestinal Peptide (VIP) se dod\u00e1v\u00e1 jako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. 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