{"id":508,"date":"2026-10-27T12:16:12","date_gmt":"2026-10-27T12:16:12","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/ara-290-10mg\/"},"modified":"2026-10-27T12:16:12","modified_gmt":"2026-10-27T12:16:12","slug":"ara-290-10mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/cs\/produkt\/ara-290-10mg\/","title":{"rendered":"ARA-290 10 mg"},"content":{"rendered":"<p>ARA-290, ozna\u010dovan\u00fd tak\u00e9 jako cibinetide, je peptid odvozen\u00fd od erytropoetinu navr\u017een tak, aby zachoval tk\u00e1\u0148ov\u011b ochrannou signalizaci bez stimulace tvorby \u010derven\u00fdch krvinek. Zkoum\u00e1 se zejm\u00e9na p\u0159i neuropatick\u00e9 bolesti, po\u0161kozen\u00ed nerv\u016f a z\u00e1n\u011btliv\u00fdch procesech. Men\u0161\u00ed klinick\u00e9 studie zkoumaly nap\u0159\u00edklad small-fiber neuropathy. V\u00fdsledky jsou zaj\u00edmav\u00e9, ale nejedn\u00e1 se o etablovanou l\u00e9\u010dbu. Peptid je v\u00fdznamn\u00fd zejm\u00e9na pro v\u00fdzkum vrozen\u00e9ho opravn\u00e9ho receptoru.<\/p>\n<h2>Co je ARA-290?<\/h2>\n<p>Z odborn\u00e9ho hlediska p\u0159edstavuje ARA-290 l\u00e1tku za\u0159azenou jako syntetick\u00fd peptid nebo peptidov\u00fd analog. Jej\u00ed experiment\u00e1ln\u00ed profil se posuzuje zejm\u00e9na p\u0159es neuropatickou bolest, small-fiber neuropathy, tk\u00e1\u0148ovou ochranu, z\u00e1n\u011bt, p\u0159i\u010dem\u017e jednotliv\u00e9 v\u00fdzkumn\u00e9 ot\u00e1zky mohou vyu\u017e\u00edvat rozd\u00edln\u00e9 bun\u011b\u010dn\u00e9, tk\u00e1\u0148ov\u00e9 nebo organismov\u00e9 modely. Sleduje se vazba na c\u00edlov\u00e9 struktury, navazuj\u00edc\u00ed signalizace a zm\u011bna vybran\u00fdch biologick\u00fdch ukazatel\u016f.<\/p>\n<h2>Mechanismus zkouman\u00e9ho p\u016fsoben\u00ed<\/h2>\n<p>ARA-290 c\u00edl\u00ed na tzv. innate repair receptor, heterokomplex souvisej\u00edc\u00ed s EPO receptorem a CD131. M\u00e1 aktivovat ochrann\u00e9 sign\u00e1ly bez klasick\u00e9 erytropoetick\u00e9 odpov\u011bdi.<\/p>\n<h2>Hlavn\u00ed oblasti v\u00fdzkumu<\/h2>\n<p><strong>\u2022&nbsp; Neuropatick\u00e1 bolest: <\/strong>ARA-290, zn\u00e1m\u00fd tak\u00e9 jako cibinetide, se zkoum\u00e1 pro tk\u00e1\u0148ov\u011b-ochrannou signalizaci spojenou s po\u0161kozen\u00edm nerv\u016f a neuropatickou bolest\u00ed.<\/p>\n<p><strong>\u2022&nbsp; Neuropatie tenk\u00fdch nervov\u00fdch vl\u00e1ken: <\/strong>Klinick\u00fd v\u00fdzkum hodnotil symptomy i hustotu drobn\u00fdch nervov\u00fdch vl\u00e1ken v k\u016f\u017ei p\u0159i small-fiber neuropathy.<\/p>\n<p><strong>\u2022&nbsp; Ochrana po\u0161kozen\u00e9 tk\u00e1n\u011b: <\/strong>Peptid byl navr\u017een tak, aby aktivoval ochrannou \u010d\u00e1st erytropoetinov\u00e9 signalizace bez stimulace tvorby \u010derven\u00fdch krvinek.<\/p>\n<p><strong>\u2022&nbsp; Z\u00e1n\u011bt nervov\u00e9 tk\u00e1n\u011b: <\/strong>V\u00fdzkum sleduje omezen\u00ed z\u00e1n\u011btliv\u00e9 odpov\u011bdi a po\u0161kozen\u00ed bun\u011bk po nervov\u00e9m nebo tk\u00e1\u0148ov\u00e9m stresu.<\/p>\n<h2>Dosavadn\u00ed zji\u0161t\u011bn\u00ed v\u00fdzkumu<\/h2>\n<p>Dosavadn\u00ed pr\u00e1ce u l\u00e1tky ARA-290 se v\u011bnuj\u00ed oblastem, mezi kter\u00e9 pat\u0159\u00ed neuropatick\u00e1 bolest, small-fiber neuropathy, tk\u00e1\u0148ov\u00e1 ochrana, z\u00e1n\u011bt. V\u00fdsledky je t\u0159eba posuzovat podle \u00farovn\u011b d\u016fkaz\u016f: bun\u011b\u010dn\u00e9 a zv\u00ed\u0159ec\u00ed modely. Men\u0161\u00ed klinick\u00e9 studie zkoumaly nap\u0159\u00edklad small-fiber neuropathy. Peptid je v\u00fdznamn\u00fd zejm\u00e9na pro v\u00fdzkum vrozen\u00e9ho opravn\u00e9ho receptoru. \u00dadaje o ne\u017e\u00e1douc\u00edch \u00fa\u010dinc\u00edch u lid\u00ed jsou omezen\u00e9 nebo z\u00e1vis\u00ed na konkr\u00e9tn\u00edm v\u00fdzkumn\u00e9m protokolu.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Produkt ARA-290 se dod\u00e1v\u00e1 jako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.<\/p>\n","protected":false},"featured_media":505,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[21],"product_tag":[39,40,41],"class_list":["post-508","product","type-product","status-publish","has-post-thumbnail","product_cat-kardiovaskularne-zdravie","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.6 (Yoast SEO v25.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ARA-290 10 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/cs\/produkt\/ara-290-10mg\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ARA-290 10 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt ARA-290 se dod\u00e1v\u00e1 jako 10 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. 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