{"id":359,"date":"2026-10-27T12:15:05","date_gmt":"2026-10-27T12:15:05","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/cjc-with-dac-5mg\/"},"modified":"2026-10-27T12:15:05","modified_gmt":"2026-10-27T12:15:05","slug":"cjc-with-dac-5mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/cs\/produkt\/cjc-with-dac-5mg\/","title":{"rendered":"CJC with DAC 5 mg"},"content":{"rendered":"<p>CJC-1295 with DAC je dlouhodob\u011b p\u016fsob\u00edc\u00ed analog GHRH navr\u017een\u00fd pro prodlou\u017een\u00ed stimulace osy r\u016fstov\u00e9ho hormonu. DAC \u010d\u00e1st umo\u017e\u0148uje vazbu na albumin a v\u00fdrazn\u011b prodlu\u017euje biologickou dostupnost molekuly. V lidsk\u00fdch studi\u00edch bylo sledov\u00e1no zv\u00fd\u0161en\u00ed GH a IGF-1. V\u00fdzkum se proto soust\u0159ed\u00ed na hormon\u00e1ln\u00ed regulaci, pulzatilitu GH a n\u00e1sledn\u00e9 metabolick\u00e9 procesy.<\/p>\n<h2>Co je CJC-1295 WITH DAC?<\/h2>\n<p>Z odborn\u00e9ho hlediska p\u0159edstavuje CJC-1295 WITH DAC l\u00e1tku za\u0159azenou jako syntetick\u00fd peptid nebo peptidov\u00fd analog. Jej\u00ed experiment\u00e1ln\u00ed profil se posuzuje zejm\u00e9na p\u0159es zv\u00fd\u0161en\u00ed GH, zv\u00fd\u0161en\u00ed IGF-1, del\u0161\u00ed trv\u00e1n\u00ed sign\u00e1lu, metabolick\u00e9 a tk\u00e1\u0148ov\u00e9 \u00fa\u010dinky osy GH, p\u0159i\u010dem\u017e jednotliv\u00e9 v\u00fdzkumn\u00e9 ot\u00e1zky mohou vyu\u017e\u00edvat rozd\u00edln\u00e9 bun\u011b\u010dn\u00e9, tk\u00e1\u0148ov\u00e9 nebo organismov\u00e9 modely. Sleduje se vazba na c\u00edlov\u00e9 struktury, navazuj\u00edc\u00ed signalizace a zm\u011bna vybran\u00fdch biologick\u00fdch ukazatel\u016f.<\/p>\n<h2>Mechanismus zkouman\u00e9ho p\u016fsoben\u00ed<\/h2>\n<p>CJC-1295 napodobuje GHRH a aktivuje GHRH receptor v hypof\u00fdze. DAC modifikace prodlu\u017euje cirkulaci molekuly vazbou na albumin.<\/p>\n<h2>Hlavn\u00ed oblasti v\u00fdzkumu<\/h2>\n<p><strong>\u2022&nbsp; Dlouhodob\u00e9 zv\u00fd\u0161en\u00ed r\u016fstov\u00e9ho hormonu: <\/strong>CJC-1295 s DAC je analog GHRH navr\u017een na prodlou\u017een\u00e9 p\u016fsoben\u00ed, proto se zkoum\u00e1 pro d\u00e9le trvaj\u00edc\u00ed zv\u00fd\u0161en\u00ed koncentrac\u00ed r\u016fstov\u00e9ho hormonu.<\/p>\n<p><strong>\u2022&nbsp; IGF-1: <\/strong>Klinick\u00fd v\u00fdzkum u zdrav\u00fdch dosp\u011bl\u00fdch uk\u00e1zal d\u00e9le p\u0159etrv\u00e1vaj\u00edc\u00ed zv\u00fd\u0161en\u00ed IGF-1, kter\u00fd pat\u0159\u00ed mezi hlavn\u00ed n\u00e1sledn\u00e9 sign\u00e1ly osy r\u016fstov\u00e9ho hormonu.<\/p>\n<p><strong>\u2022&nbsp; Prodlou\u017een\u00e9 p\u016fsoben\u00ed DAC: <\/strong>DAC umo\u017e\u0148uje vazbu na albumin a v\u00fdrazn\u011b prodlu\u017euje biologick\u00e9 p\u016fsoben\u00ed molekuly oproti kr\u00e1tkodob\u011bj\u0161\u00edm GHRH analog\u016fm.<\/p>\n<p><strong>\u2022&nbsp; Osa GH\/IGF-1: <\/strong>CJC-1295 se pou\u017e\u00edv\u00e1 ke zkoum\u00e1n\u00ed toho, jak dlouhodob\u00e1 stimulace GHRH receptoru m\u011bn\u00ed hormon\u00e1ln\u00ed profil GH a IGF-1 v \u010dase.<\/p>\n<h2>Dosavadn\u00ed zji\u0161t\u011bn\u00ed v\u00fdzkumu<\/h2>\n<p>Dosavadn\u00ed pr\u00e1ce u l\u00e1tky CJC-1295 WITH DAC se v\u011bnuj\u00ed oblastem, mezi kter\u00e9 pat\u0159\u00ed zv\u00fd\u0161en\u00ed GH, zv\u00fd\u0161en\u00ed IGF-1, del\u0161\u00ed trv\u00e1n\u00ed sign\u00e1lu, metabolick\u00e9 a tk\u00e1\u0148ov\u00e9 \u00fa\u010dinky osy GH. V\u00fdzkum se proto soust\u0159ed\u00ed na hormon\u00e1ln\u00ed regulaci, pulzatilitu GH a n\u00e1sledn\u00e9 metabolick\u00e9 procesy.<\/p>\n<p>Ve studi\u00edch CJC-1295 byly sledov\u00e1ny reakce v m\u00edst\u011b pod\u00e1n\u00ed, zarudnut\u00ed, bolest hlavy a hormon\u00e1ln\u00ed zm\u011bny souvisej\u00edc\u00ed se zv\u00fd\u0161en\u00edm GH a IGF-1.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Produkt CJC with DAC se dod\u00e1v\u00e1 jako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.<\/p>\n","protected":false},"featured_media":356,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[16],"product_tag":[39,40,41],"class_list":["post-359","product","type-product","status-publish","has-post-thumbnail","product_cat-regeneracia-a-vykon","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.6 (Yoast SEO v25.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>CJC with DAC 5 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/cs\/produkt\/cjc-with-dac-5mg\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CJC with DAC 5 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt CJC with DAC se dod\u00e1v\u00e1 jako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. 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