{"id":338,"date":"2026-10-27T12:14:55","date_gmt":"2026-10-27T12:14:55","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/aod-9604-5mg\/"},"modified":"2026-10-27T12:14:55","modified_gmt":"2026-10-27T12:14:55","slug":"aod-9604-5mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/cs\/produkt\/aod-9604-5mg\/","title":{"rendered":"AOD-9604 5 mg"},"content":{"rendered":"<p>AOD-9604 je modifikovan\u00fd fragment C-koncov\u00e9 \u010d\u00e1sti lidsk\u00e9ho r\u016fstov\u00e9ho hormonu vyv\u00edjen\u00fd zejm\u00e9na pro v\u00fdzkum metabolismu tuk\u016f a obezity. Byl navr\u017een tak, aby napodoboval \u010d\u00e1st lipolytick\u00fdch \u00fa\u010dink\u016f GH bez pln\u00e9 r\u016fstov\u00e9 aktivity hormonu. P\u0159edklinick\u00e9 pr\u00e1ce ukazovaly vliv na lipol\u00fdzu a lipogenezi. Pozd\u011bji se zkoumal i v dal\u0161\u00edch tk\u00e1\u0148ov\u00fdch modelech.<\/p>\n<h2>Co je AOD-9604?<\/h2>\n<p>AOD-9604 se \u0159ad\u00ed mezi l\u00e1tky typu \u201esyntetick\u00fd peptid nebo peptidov\u00fd analog\u201c a v odborn\u00e9m v\u00fdzkumu se hodnot\u00ed v souvislosti s oblastmi jako metabolismus tuk\u016f, lipol\u00fdza, lipogeneze, t\u011blesn\u00e1 hmotnost. Pozornost se v\u011bnuje jeho interakci s p\u0159\u00edslu\u0161n\u00fdmi receptory, enzymy nebo bun\u011b\u010dn\u00fdmi dr\u00e1hami a n\u00e1sledn\u00fdm zm\u011bn\u00e1m m\u011b\u0159iteln\u00fdch laboratorn\u00edch parametr\u016f.<\/p>\n<h2>Mechanismus zkouman\u00e9ho p\u016fsoben\u00ed<\/h2>\n<p>AOD-9604 je modifikovan\u00fd fragment GH 176-191. M\u00e1 zachovat metabolickou signalizaci spojenou s tukem bez pln\u00e9 aktivace r\u016fstov\u00e9ho hormonov\u00e9ho receptoru.<\/p>\n<h2>Hlavn\u00ed oblasti v\u00fdzkumu<\/h2>\n<p><strong>\u2022&nbsp; Metabolismus tuk\u016f: <\/strong>AOD-9604 je modifikovan\u00fd fragment C-koncov\u00e9 \u010d\u00e1sti r\u016fstov\u00e9ho hormonu zkouman\u00fd pro metabolick\u00e9 procesy v tukov\u00e9 tk\u00e1ni.<\/p>\n<p><strong>\u2022&nbsp; Lipol\u00fdza: <\/strong>P\u0159edklinick\u00fd v\u00fdzkum se v\u011bnuje mobilizaci ulo\u017een\u00e9ho tuku a uvol\u0148ov\u00e1n\u00ed mastn\u00fdch kyselin z adipocyt\u016f.<\/p>\n<p><strong>\u2022&nbsp; Lipogeneze: <\/strong>Sou\u010dasn\u011b se zkoum\u00e1 vliv na tvorbu a ukl\u00e1d\u00e1n\u00ed nov\u00fdch z\u00e1sob tuku, aby se odd\u011blily metabolick\u00e9 \u00fa\u010dinky od r\u016fstov\u00fdch \u00fa\u010dink\u016f cel\u00e9ho GH.<\/p>\n<p><strong>\u2022&nbsp; T\u011blesn\u00e1 hmotnost: <\/strong>AOD-9604 byl zkoum\u00e1n i v klinick\u00e9m v\u00fdvoji pro obezitu, av\u0161ak dostupn\u00e9 v\u00fdsledky nepotvrdily konzistentn\u00ed klinick\u00fd \u00fa\u010dinek na redukci hmotnosti.<\/p>\n<p><strong>\u2022&nbsp; Chrupavka: <\/strong>Samostatn\u00fd p\u0159edklinick\u00fd sm\u011br zkoum\u00e1 AOD-9604 v modelech po\u0161kozen\u00ed chrupavky a osteoartr\u00f3zy.<\/p>\n<h2>Dosavadn\u00ed zji\u0161t\u011bn\u00ed v\u00fdzkumu<\/h2>\n<p>V\u00fdsledky je t\u0159eba posuzovat podle \u00farovn\u011b d\u016fkaz\u016f: bun\u011b\u010dn\u00e9 a zv\u00ed\u0159ec\u00ed. AOD-9604 je modifikovan\u00fd fragment C-koncov\u00e9 \u010d\u00e1sti lidsk\u00e9ho r\u016fstov\u00e9ho hormonu vyv\u00edjen\u00fd zejm\u00e9na pro v\u00fdzkum metabolismu tuk\u016f a obezity. P\u0159edklinick\u00e9 pr\u00e1ce ukazovaly vliv na lipol\u00fdzu a lipogenezi, ale klinick\u00e9 v\u00fdsledky p\u0159i redukci hmotnosti neprok\u00e1zaly p\u0159esv\u011bd\u010div\u00fd \u00fa\u010dinek pot\u0159ebn\u00fd pro etablovanou l\u00e9\u010dbu obezity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Produkt AOD-9604 se dod\u00e1v\u00e1 jako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.<\/p>\n","protected":false},"featured_media":335,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[17],"product_tag":[39,40,41],"class_list":["post-338","product","type-product","status-publish","has-post-thumbnail","product_cat-kontrola-hmotnosti","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.6 (Yoast SEO v25.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>AOD-9604 5 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/cs\/produkt\/aod-9604-5mg\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"AOD-9604 5 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt AOD-9604 se dod\u00e1v\u00e1 jako 5 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. 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