{"id":333,"date":"2026-10-27T12:14:53","date_gmt":"2026-10-27T12:14:53","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/aicar-50mg\/"},"modified":"2026-10-27T12:14:53","modified_gmt":"2026-10-27T12:14:53","slug":"aicar-50mg","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/","title":{"rendered":"AICAR 50 mg"},"content":{"rendered":"

AICAR – jedn\u00e1 se o experiment\u00e1ln\u00ed purinovou slou\u010deninu pou\u017e\u00edvanou zejm\u00e9na k aktivaci AMPK. AMPK je kl\u00ed\u010dov\u00fd bun\u011b\u010dn\u00fd senzor energetick\u00e9ho stavu, proto se AICAR pou\u017e\u00edv\u00e1 ve v\u00fdzkumu metabolismu gluk\u00f3zy, mastn\u00fdch kyselin a mitochondri\u00e1ln\u00ed adaptace. Zn\u00e1m\u00fd je i z experiment\u016f fyzick\u00e9 v\u00fdkonnosti a \u201eexercise mimetic\u201c mechanism\u016f.<\/p>\n

Co je AICAR?<\/h2>\n

Z odborn\u00e9ho hlediska p\u0159edstavuje AICAR l\u00e1tku za\u0159azenou jako mal\u00e1 syntetick\u00e1 molekula. Jej\u00ed experiment\u00e1ln\u00ed profil se posuzuje zejm\u00e9na p\u0159es AMPK, metabolismus gluk\u00f3zy, oxidace mastn\u00fdch kyselin, mitochondri\u00e1ln\u00ed adaptace, p\u0159i\u010dem\u017e jednotliv\u00e9 v\u00fdzkumn\u00e9 ot\u00e1zky mohou vyu\u017e\u00edvat rozd\u00edln\u00e9 bun\u011b\u010dn\u00e9, tk\u00e1\u0148ov\u00e9 nebo organismov\u00e9 modely. Sleduje se vazba na c\u00edlov\u00e9 struktury, navazuj\u00edc\u00ed signalizace a zm\u011bna vybran\u00fdch biologick\u00fdch ukazatel\u016f.<\/p>\n

Mechanismus zkouman\u00e9ho p\u016fsoben\u00ed<\/h2>\n

AICAR se v bu\u0148k\u00e1ch p\u0159em\u011b\u0148uje na ZMP, analog AMP, kter\u00fd m\u016f\u017ee aktivovat AMPK a t\u00edm m\u011bnit energetick\u00fd metabolismus. M\u00e1 tak\u00e9 AMPK-nez\u00e1visl\u00e9 \u00fa\u010dinky.<\/p>\n

Hlavn\u00ed oblasti v\u00fdzkumu<\/h2>\n

\u2022  Aktivace AMPK: <\/strong>AICAR se v bu\u0148k\u00e1ch p\u0159em\u011b\u0148uje na ZMP, kter\u00fd napodobuje energetick\u00fd sign\u00e1l AMP a aktivuje AMPK \u2013 hlavn\u00ed senzor n\u00edzk\u00e9 dostupnosti energie.<\/p>\n

\u2022  Metabolismus gluk\u00f3zy: <\/strong>V\u00fdzkum sleduje, jak aktivace AMPK m\u011bn\u00ed p\u0159\u00edjem a vyu\u017eit\u00ed gluk\u00f3zy zejm\u00e9na v kostern\u00edm svalstvu.<\/p>\n

\u2022  Oxidace mastn\u00fdch kyselin: <\/strong>AICAR se pou\u017e\u00edv\u00e1 ke zkoum\u00e1n\u00ed p\u0159epnut\u00ed metabolismu sm\u011brem k vy\u0161\u0161\u00edmu vyu\u017e\u00edv\u00e1n\u00ed mastn\u00fdch kyselin jako zdroje energie.<\/p>\n

\u2022  Mitochondri\u00e1ln\u00ed adaptace: <\/strong>Del\u0161\u00ed aktivace AMPK se zkoum\u00e1 v souvislosti s tvorbou a funk\u010dn\u00ed adaptac\u00ed mitochondri\u00ed.<\/p>\n

\u2022  Vytrvalostn\u00ed adaptace: <\/strong>P\u0159edklinick\u00e9 modely zkoumaj\u00ed metabolick\u00e9 zm\u011bny podobn\u00e9 \u010d\u00e1sti adapta\u010dn\u00ed odpov\u011bdi na vytrvalostn\u00ed z\u00e1t\u011b\u017e; AICAR p\u0159itom nen\u00ed peptid.<\/p>\n

Dosavadn\u00ed zji\u0161t\u011bn\u00ed v\u00fdzkumu<\/h2>\n

V\u00fdsledky je t\u0159eba posuzovat podle \u00farovn\u011b d\u016fkaz\u016f: bun\u011b\u010dn\u00e9 a zv\u00ed\u0159ec\u00ed modely. AMPK je kl\u00ed\u010dov\u00fd bun\u011b\u010dn\u00fd senzor energetick\u00e9ho stavu, proto se AICAR pou\u017e\u00edv\u00e1 ve v\u00fdzkumu metabolismu gluk\u00f3zy, mastn\u00fdch kyselin a mitochondri\u00e1ln\u00ed adaptace. V\u011bt\u0161ina takov\u00fdch v\u00fdsledk\u016f je preklinick\u00e1.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produkt AICAR se dod\u00e1v\u00e1 jako 50 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.<\/p>\n","protected":false},"featured_media":330,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[16],"product_tag":[39,40,41],"class_list":["post-333","product","type-product","status-publish","has-post-thumbnail","product_cat-regeneracia-a-vykon","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nAICAR 50 mg - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"AICAR 50 mg\" \/>\n<meta property=\"og:description\" content=\"Produkt AICAR se dod\u00e1v\u00e1 jako 50 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/\" \/>\n<meta property=\"og:site_name\" content=\"VirexionLabs.net\" \/>\n<meta property=\"og:image\" content=\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Cena\" \/>\n\t<meta name=\"twitter:data1\" content=\"50,00 €\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dostupnost\" \/>\n\t<meta name=\"twitter:data2\" content=\"Skladem\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/\",\"url\":\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/\",\"name\":\"AICAR 50 mg - VirexionLabs.net\",\"isPartOf\":{\"@id\":\"https:\/\/virexionlabs.net\/cs\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp\",\"datePublished\":\"2026-10-27T12:14:53+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#breadcrumb\"},\"inLanguage\":\"cs\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"cs\",\"@id\":\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#primaryimage\",\"url\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp\",\"contentUrl\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp\",\"width\":1024,\"height\":1024,\"caption\":\"AICAR 50 mg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/virexionlabs.net\/cs\/domov-2\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Obchod\",\"item\":\"https:\/\/virexionlabs.net\/cs\/obchod\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"AICAR 50 mg\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/virexionlabs.net\/cs\/#website\",\"url\":\"https:\/\/virexionlabs.net\/cs\/\",\"name\":\"VirexionLabs.com\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/virexionlabs.net\/cs\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/virexionlabs.net\/cs\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"cs\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/virexionlabs.net\/cs\/#organization\",\"name\":\"VirexionLabs.com\",\"url\":\"https:\/\/virexionlabs.net\/cs\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"cs\",\"@id\":\"https:\/\/virexionlabs.net\/cs\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png\",\"contentUrl\":\"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png\",\"width\":2172,\"height\":724,\"caption\":\"VirexionLabs.com\"},\"image\":{\"@id\":\"https:\/\/virexionlabs.net\/cs\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<meta property=\"product:price:amount\" content=\"50.00\" \/>\n<meta property=\"product:price:currency\" content=\"EUR\" \/>\n<meta property=\"og:availability\" content=\"instock\" \/>\n<meta property=\"product:availability\" content=\"instock\" \/>\n<meta property=\"product:retailer_item_id\" content=\"VX-AICAR-50MG\" \/>\n<meta property=\"product:condition\" content=\"new\" \/>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"AICAR 50 mg - VirexionLabs.net","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/","og_locale":"cs_CZ","og_type":"article","og_title":"AICAR 50 mg","og_description":"Produkt AICAR se dod\u00e1v\u00e1 jako 50 mg lyofilizovan\u00fd pr\u00e1\u0161ek v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.","og_url":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/","og_site_name":"VirexionLabs.net","og_image":[{"width":1024,"height":1024,"url":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp","type":"image\/webp"}],"twitter_card":"summary_large_image","twitter_misc":{"Cena":"50,00 €","Dostupnost":"Skladem"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/","url":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/","name":"AICAR 50 mg - VirexionLabs.net","isPartOf":{"@id":"https:\/\/virexionlabs.net\/cs\/#website"},"primaryImageOfPage":{"@id":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#primaryimage"},"image":{"@id":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#primaryimage"},"thumbnailUrl":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp","datePublished":"2026-10-27T12:14:53+00:00","breadcrumb":{"@id":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#breadcrumb"},"inLanguage":"cs","potentialAction":[{"@type":"ReadAction","target":["https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/"]}]},{"@type":"ImageObject","inLanguage":"cs","@id":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#primaryimage","url":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp","contentUrl":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/26_AICAR_50_mg-muwppi05-kttq-1024w.webp","width":1024,"height":1024,"caption":"AICAR 50 mg"},{"@type":"BreadcrumbList","@id":"https:\/\/virexionlabs.net\/cs\/produkt\/aicar-50mg\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/virexionlabs.net\/cs\/domov-2\/"},{"@type":"ListItem","position":2,"name":"Obchod","item":"https:\/\/virexionlabs.net\/cs\/obchod\/"},{"@type":"ListItem","position":3,"name":"AICAR 50 mg"}]},{"@type":"WebSite","@id":"https:\/\/virexionlabs.net\/cs\/#website","url":"https:\/\/virexionlabs.net\/cs\/","name":"VirexionLabs.com","description":"","publisher":{"@id":"https:\/\/virexionlabs.net\/cs\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/virexionlabs.net\/cs\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"cs"},{"@type":"Organization","@id":"https:\/\/virexionlabs.net\/cs\/#organization","name":"VirexionLabs.com","url":"https:\/\/virexionlabs.net\/cs\/","logo":{"@type":"ImageObject","inLanguage":"cs","@id":"https:\/\/virexionlabs.net\/cs\/#\/schema\/logo\/image\/","url":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png","contentUrl":"https:\/\/virexionlabs.net\/wp-content\/uploads\/2026\/10\/logowithoutbg-mue86pzb-t1luuu.png","width":2172,"height":724,"caption":"VirexionLabs.com"},"image":{"@id":"https:\/\/virexionlabs.net\/cs\/#\/schema\/logo\/image\/"}}]},"product_price_amount":"50.00","product_price_currency":"EUR","og_availability":"instock","product_availability":"instock","product_retailer_item_id":"VX-AICAR-50MG","product_condition":"new"},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/product\/333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/comments?post=333"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/media\/330"}],"wp:attachment":[{"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/media?parent=333"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/product_brand?post=333"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/product_cat?post=333"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/virexionlabs.net\/cs\/wp-json\/wp\/v2\/product_tag?post=333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}