{"id":298,"date":"2026-10-27T12:14:36","date_gmt":"2026-10-27T12:14:36","guid":{"rendered":"https:\/\/virexionlabs.net\/product\/hcg-5000iu\/"},"modified":"2026-10-27T12:14:36","modified_gmt":"2026-10-27T12:14:36","slug":"hcg-5000iu","status":"publish","type":"product","link":"https:\/\/virexionlabs.net\/cs\/produkt\/hcg-5000iu\/","title":{"rendered":"HCG 5000 IU"},"content":{"rendered":"

HCG je v\u00fdzkumn\u00e1 formulace obsahuj\u00edc\u00ed 5000 IU lidsk\u00e9ho choriov\u00e9ho gonadotropinu. Tento glykoproteinov\u00fd hormon se v laboratorn\u00edch modelech zkoum\u00e1 zejm\u00e9na v souvislosti s receptorem LH\/HCG, steroidogenez\u00ed a reproduk\u010dn\u00ed endokrinologi\u00ed.<\/p>\n

Co je HCG?<\/h2>\n

HCG, tedy lidsk\u00fd choriov\u00fd gonadotropin, je heterodimern\u00ed glykoproteinov\u00fd hormon tvo\u0159en\u00fd alfa a beta podjednotkou. Nen\u00ed klasick\u00fdm kr\u00e1tk\u00fdm syntetick\u00fdm peptidem. P\u0159irozen\u011b jej produkuje zejm\u00e9na placent\u00e1rn\u00ed tk\u00e1\u0148 a biologicky p\u016fsob\u00ed prost\u0159ednictv\u00edm spole\u010dn\u00e9ho receptoru pro luteiniza\u010dn\u00ed hormon a HCG. Deklarace 5000 IU vyjad\u0159uje biologickou aktivitu, nikoli hmotnost l\u00e1tky.<\/p>\n

Mechanismus zkouman\u00e9ho p\u016fsoben\u00ed<\/h2>\n

HCG se v\u00e1\u017ee na receptor LH\/HCG, kter\u00fd pat\u0159\u00ed mezi receptory spojen\u00e9 s G-proteinem. Aktivace receptoru zvy\u0161uje tvorbu cAMP a spou\u0161t\u00ed intracelul\u00e1rn\u00ed dr\u00e1hy souvisej\u00edc\u00ed se steroidogenez\u00ed. V experiment\u00e1ln\u00edch modelech se n\u00e1sledn\u011b sleduje tvorba steroidn\u00edch hormon\u016f, funkce gonad\u00e1ln\u00edch bun\u011bk a receptorov\u00e1 odpov\u011b\u010f v r\u016fzn\u00fdch tk\u00e1n\u00edch.<\/p>\n

HLAVN\u00cd OBLASTI V\u00ddZKUMU<\/h2>\n

\u2022  Signalizace receptoru LH\/hCG:<\/strong> Zkoum\u00e1 se vazba hormonu na receptor, aktivace cAMP, fosforylace navazuj\u00edc\u00edch protein\u016f a \u010dasov\u00fd pr\u016fb\u011bh bun\u011b\u010dn\u00e9 odpov\u011bdi.<\/p>\n

\u2022  Steroidogeneze:<\/strong> Laboratorn\u00ed modely hodnot\u00ed zm\u011bny synt\u00e9zy progesteronu, testosteronu a dal\u0161\u00edch steroidn\u00edch hormon\u016f po aktivaci bun\u011bk exprimuj\u00edc\u00edch receptor LH\/hCG.<\/p>\n

\u2022  Ovari\u00e1ln\u00ed bun\u011b\u010dn\u00e9 procesy:<\/strong> P\u0159edm\u011btem v\u00fdzkumu jsou reakce granul\u00f3zov\u00fdch a tek\u00e1ln\u00edch bun\u011bk, luteinizace a mechanismy souvisej\u00edc\u00ed s zr\u00e1n\u00edm folikulu.<\/p>\n

\u2022  Funkce Leydigov\u00fdch bun\u011bk:<\/strong> Sleduje se receptorov\u00e1 signalizace, exprese steroidogenn\u00edch enzym\u016f a hormon\u00e1ln\u00ed odpov\u011b\u010f v mu\u017esk\u00fdch reproduk\u010dn\u00edch modelech.<\/p>\n

Dosavadn\u00ed zji\u0161t\u011bn\u00ed v\u00fdzkumu<\/h2>\n

Biologick\u00e1 role HCG a jeho vazba na receptor LH\/HCG jsou dob\u0159e charakterizov\u00e1ny. V\u00fdzkum potvrdil, \u017ee hormon ovliv\u0148uje steroidogenezi a reproduk\u010dn\u00ed bun\u011b\u010dn\u00e9 procesy, p\u0159i\u010dem\u017e jeho \u00fa\u010dinek z\u00e1vis\u00ed na biologick\u00e9 aktivit\u011b, glykosylaci, zkouman\u00e9 tk\u00e1ni a experiment\u00e1ln\u00edch podm\u00ednk\u00e1ch.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produkt HCG se dod\u00e1v\u00e1 jako lyofilizovan\u00fd pr\u00e1\u0161ek s deklarovanou aktivitou 5000 IU v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. Nen\u00ed ur\u010den pro hum\u00e1nn\u00ed ani veterin\u00e1rn\u00ed pou\u017eit\u00ed.<\/p>\n","protected":false},"featured_media":295,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[22],"product_tag":[39,40,41],"class_list":["post-298","product","type-product","status-publish","has-post-thumbnail","product_cat-vyskumne-serie","product_tag-lyophilised","product_tag-research-use-only","product_tag-third-party-tested","first","instock","featured","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nHCG 5000 IU - VirexionLabs.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/virexionlabs.net\/cs\/produkt\/hcg-5000iu\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HCG 5000 IU\" \/>\n<meta property=\"og:description\" content=\"Produkt HCG se dod\u00e1v\u00e1 jako lyofilizovan\u00fd pr\u00e1\u0161ek s deklarovanou aktivitou 5000 IU v uzav\u0159en\u00e9 sklen\u011bn\u00e9 vialce. Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. 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Ur\u010den v\u00fdhradn\u011b pro laboratorn\u00ed v\u00fdzkum. 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